International Journal of Pharmaceutical Research and Nanotechnology

Author: Rohit Singh

Abstract: Nanostructured materials have revolutionized the field of oral drug delivery, offering new ways to address the challenges of drug solubility and controlled release. This paper explores the use of nanomaterials, particularly in enhancing the solubility of poorly water-soluble drugs and providing a controlled release mechanism. The use of nanocarriers such as liposomes, dendrimers, and nanoparticles has been extensively researched for their ability to improve bioavailability and reduce side effects. We discuss the mechanisms behind controlled release, the types of nanomaterials used, and the methods of fabrication. The paper also highlights recent advances in the development of novel nanostructured carriers, their advantages over conventional delivery systems, and the challenges they face in clinical application.

Keywords: Nanostructured Materials, Controlled Release, Oral Drug Delivery, Drug Solubility, Nanocarriers, Liposomes, Dendrimers, Nanoparticles, Bioavailability, Pharmaceutical Nanotechnology.