Journal of Research in Applied Chemistry

Authors :  Anil Kumar, Meena Sharma

Abstract : Nanotechnology has revolutionized the field of drug delivery by enabling the design and synthesis of nanoscale carriers that can improve the efficacy and targeting of therapeutic agents. This paper investigates the design, synthesis, and applications of various nanocarriers, including liposomes, polymeric nanoparticles, and dendrimers, for drug delivery. We employed techniques such as nanoprecipitation, emulsion polymerization, and self-assembly to synthesize these nanocarriers. Characterization methods, including dynamic light scattering (DLS), transmission electron microscopy (TEM), and zeta potential measurements, were used to analyze their size, morphology, and surface charge. The drug loading capacity, release kinetics, and targeting efficiency of these nanocarriers were evaluated in vitro and in vivo. The results demonstrate enhanced drug solubility, stability, and controlled release, as well as improved targeting to specific tissues and cells. Additionally, the potential of these nanocarriers to reduce side effects and improve patient compliance was assessed, highlighting their promise in advancing personalized medicine.

Keywords : Nanotechnology, Drug delivery, Nanocarriers, Targeted therapy, Personalized medicine