Author: Neha Patel
Abstract: The optimization of drug delivery systems to prolong drug release and maintain therapeutic levels in the bloodstream is a critical aspect of pharmacotherapy. This paper reviews various strategies employed to enhance drug stability, control release kinetics, and achieve sustained therapeutic efficacy. Techniques such as the development of novel polymeric matrices, incorporation of micro- and nanotechnologies, use of lipid-based formulations, and application of smart drug delivery systems are explored. Additionally, the role of bioengineering approaches, such as hydrogels and micelles, as well as the use of controlled-release technologies like osmotic pumps and reservoir systems, are discussed. The review highlights the advantages and challenges associated with these strategies, providing insights into their potential applications in clinical settings to improve patient outcomes and reduce side effects.
Keywords: Drug delivery, sustained release, polymeric matrices, nanotechnology, lipid-based formulations, controlled-release systems, therapeutic efficacy, hydrogels, osmotic pumps.
Full Issue
| View or download the full issue | PDF 11-17 |