Authors : Dr. Priya Menon, Rahul Verma
Abstract: Autoimmune diseases arise when the immune system mounts a response against self-antigens. Cross-reactivity and molecular mimicry are critical mechanisms through which infections or environmental triggers provoke autoimmune responses. This paper reviews the molecular basis of cross reactivity, its contribution to autoimmunity, and clinical examples where molecular mimicry leads to disease. A table summarizing notable pathogens, self-antigens, and associated autoimmune disorders is provided. Understanding these mechanisms is essential for developing preventive strategies, diagnostics, and therapeutics to mitigate autoimmune disease progression.
Keywords: Autoimmunity, cross-reactivity, molecular mimicry, self-antigens, autoimmune diseases, immune tolerance, pathogen-induced autoimmunity
Full Issue
| View or download the full issue | PDF 7-11 |