Vol 3, No 2 (2021)

Molecular Iodine: A Novel Broad-Spectrum Antiviral Agent against SARS-Cov-2

Authors: Srikanta Akumalla, Hamsini Hari kumar, Maithri D. B, Aditi S. Jois

Abstract: Corona viruses are a group of RNA viruses that cause respiratory infection in mammals and birds. The ongoing COVID-19 pandemic has heightened the battle between humans and viruses. At this time, it is critical for everyone to take precautionary measures in order to avoid becoming infected. Physical barriers, such as masks, PPE kits, and face-shields, as well as maintaining social distance, are recommended. Chemical barriers, such as hand sanitizers, sprays, and hand-washes, are also recommended along with vaccinations. Another lesser-known but well-proven method for combating Covid is to use Iodine as an antiviral agent. Iodine has broad-spectrum disinfectant properties. According to laboratory studies, iodine exposure inactivates the SARS virus within few minutes. Iodine can be taken in the form of Povidone-iodine (PVP-I) gargles or Iodine V (available in the form of Essential Iodine Drops) or the use of molecular iodine (I2) in the form of lotion (I2 Cure). Iodine acts on viruses by damaging viral surface proteins and lipid coating. Free iodine can cause irreversible damage to the virus by degrading viral nucleoproteins, oxidising nucleic acids, and disrupting metabolic pathways. Furthermore, free iodine is an anti-inflammatory agent during viral infections because it scavenges free radicals. Iodine's above action results in the inactivation of the cell/viral particle. Although the use of iodine seems as a promising method of inactivating viruses, the effects of long-term exposure to Iodine is not fully evaluated.

The purpose of this paper is to understand a relatively unknown but well-proven mode of disinfection, namely the use of molecular iodine, against Corona virus.

Keywords: COVID, Molecular Iodine, Antiviral agent, Antimicrobial Agent, SARS-CoV-2

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