Vol 6, No 2 (2024)

The Impact of Pharmaceutical Excipients on Drug Formulation and Delivery

Authors: Neha Rani, Amit Verma, Priya Agarwal

Abstract: Pharmaceutical excipients play a crucial role in drug formulation and delivery, influencing the stability, bioavailability, and overall effectiveness of medications. This paper provides an in-depth analysis of the various types of excipients used in pharmaceutical formulations, including binders, fillers, disintegrants, lubricants, and preservatives. We discuss the functional properties of these excipients and their impact on drug formulation, focusing on their role in enhancing drug solubility, stability, and release profiles. Additionally, we explore the regulatory considerations and safety profiles of commonly used excipients. Understanding the critical role of excipients in drug formulation is essential for developing safe, effective, and high-quality pharmaceuticals.

Keywords: Excipients, Drug Formulation, Bioavailability, Stability, Release Profiles.

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