Authors: Dr. Ritu Gupta, Sonali Negi
Abstract: The drug compounds under investigation have previously been used to treat restenosis and various diabetic complications. They have demonstrated potential in treating conditions such as rheumatoid arthritis, atherosclerosis, cirrhosis, fibrosis, autoimmune diseases, and cancer. While the cytotoxicity of these compounds is already established, this study focuses on a comparative analysis of all three compounds together. The significance of cancer treatment research is paramount, given the high annual mortality rate from the disease. This study revisits earlier drugs with the aim of optimizing their characteristics. Among the compounds, Compound A exhibited significantly higher cytotoxicity than Compounds B and C, although the latter two were also effective to a lesser extent. The activities of these compounds can be optimized by considering factors such as potency, selectivity, and toxicity effects.
Keywords: Cancer chemotherapy, Drug design, cancer, drug interactions, pharmacodynamics, organic synthesis optimization
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