Authors: Dr. Sneha Kapoor, Dr. Rohan Mehra
Abstract: Herbal and phytopharmaceuticals have gained significant attention due to their therapeutic potential, safety profile, and natural origin. However, challenges such as poor solubility, stability issues, low bioavailability, and variability in phytoconstituent content limit their clinical efficacy. This paper reviews modern formulation strategies for herbal and phytopharmaceutical products, including solid dosage forms, micro- and nanoencapsulation, self emulsifying systems, and sustained release formulations. Approaches to improve stability, solubility, and controlled release are discussed. Analytical techniques for standardization, quality control, and bioavailability assessment are highlighted. Tables summarize key strategies, their mechanisms, and advantages. Case studies of marketed phytopharmaceutical products illustrate practical applications. Regulatory considerations and future trends in personalized herbal formulations are also explored.
Keywords: Herbal formulations, Phytopharmaceuticals, Nanoencapsulation, Self-emulsifying systems, Bioavailability, Stability, Controlled release.
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