Vol 4, No 3 (2022)

Formulation of Liposomes and Niosomes for Targeted Therapy

Authors: Dr. Meenal Sharma, Mr. Karan Malhotra

ABSTRACT: Liposomes and niosomes are widely researched vesicular systems in modern pharmaceutics due to their potential in improving drug targeting, enhancing therapeutic efficacy, and reducing systemic side effects. These nanocarriers can encapsulate both hydrophilic and hydrophobic drugs, making them versatile tools in treating chronic diseases, cancer, and infections. Liposomes are phospholipid-based vesicles, while niosomes are formed using non-ionic surfactants, each offering unique advantages in formulation, stability, and cost-effectiveness. This paper provides a comprehensive discussion on the formulation strategies, preparation methods, characterization techniques, therapeutic applications, comparative analysis, challenges, and future perspectives of liposomes and niosomes in targeted therapy.

Keywords: Liposomes, Niosomes, Targeted Therapy, Nanocarriers, Drug Delivery Systems, Formulation

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