Vol 6, No 2 (2024)

Application of Nuclear Magnetic Resonance (NMR) Spectroscopy in Drug Research

Authors: Karan Singh, Sonia Mehta

Abstract: Nuclear Magnetic Resonance (NMR) spectroscopy is a powerful analytical technique widely used in pharmaceutical analysis and drug research. Its ability to provide detailed structural information about molecules makes it invaluable for the identification, quantification, and characterization of pharmaceutical compounds. This paper examines the applications of NMR spectroscopy in drug research, highlighting its role in structural elucidation, impurity profiling, and drug interaction studies. The advancements in NMR technology, such as high-field NMR and cryoprobe technology, and their impact on enhancing drug research are also discussed. Additionally, the paper explores the challenges and future directions of NMR spectroscopy in pharmaceutical analysis.

Keywords: Nuclear Magnetic Resonance (NMR) Spectroscopy, Structural Elucidation, Impurity Profiling, Drug Interaction Studies, High-Field NMR

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