Vol 6, No 2 (2024)

Role of Mass Spectrometry in Pharmaceutical Analysis and Drug Development

Author: Sunil Gupta

Abstract: Mass spectrometry (MS) has emerged as a powerful analytical tool in pharmaceutical analysis and drug development. Its ability to provide detailed molecular information with high sensitivity and accuracy makes it indispensable in the identification, quantification, and structural elucidation of pharmaceutical compounds. This paper delves into the various applications of mass spectrometry in the pharmaceutical industry, including its role in drug metabolism studies, pharmacokinetics, and quality control. Additionally, the paper discusses recent advancements in MS technology, such as tandem mass spectrometry (MS/MS) and high-resolution mass spectrometry (HRMS), and their impact on enhancing drug research. The challenges and future prospects of MS in pharmaceutical analysis are also explored.

Keywords: Mass Spectrometry (MS), Tandem Mass Spectrometry (MS/MS), High-Resolution Mass Spectrometry (HRMS), Drug Metabolism, Pharmacokinetics

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