Journal of Pharmaceutical Analysis and Drug Research ISSN: 3108-0839 (Online)

Authors: Disha Pal, Gaurav Saksena

Abstract: Targeted therapy has emerged as a promising approach in cancer treatment, aiming to selectively attack cancer cells while minimizing damage to healthy tissues. This paper explores the mechanisms and strategies behind the development of drugs that specifically target cancer cells, such as monoclonal antibodies, small molecule inhibitors, antibody-drug conjugates, and cancer vaccines. Benefits include increased specificity, reduced toxicity, and the potential for personalized medicine. However, challenges like resistance development and tumor heterogeneity underscore the need for continued research and innovation. Future directions include biomarker discovery, combination therapies, gene editing, RNA-based therapies, and nanotechnology, offering hope for more effective and less harmful cancer treatments.

Keywords: Targeted therapy, cancer treatment, monoclonal antibodies, small molecule inhibitors, antibody-drug conjugates, cancer vaccines, personalized medicine, resistance, biomarkers, combination therapy, gene editing, nanotechnology