Journal of Pharmaceutical Analysis and Drug Research ISSN: 3108-0839 (Online)

Authors:- Ranjeet Singh, Dr. Shivsankar Prasad

Abstract:- Many pharmacological entities based on oral delivery have been successfully marketed, but many others are not easily accessible by oral administration due to incompatibility with the physical and chemical conditions of the upper gastrointestinal tract (GIT) and inadequate absorption in the GIT. Because of the absence of digestive enzymes, the colon is thought to be a good place for medication absorption. The key difficulty for scientists over the last two decades has been to target medications particularly to the colonic portion of the GIT. Previously, the colon was thought to be a harmless organ responsible only for the absorption of water, electrolytes, and the temporary storage of faeces. However, it is increasingly recognised as a significant location for medication delivery. This review concentrated on various methods of colonic delivery and significant uses of colonic medication delivery systems.

Keywords:- Colon, Drug Delivery System, upper gastrointestinal tract (GIT).