Journal of Pharmaceutical Analysis and Drug Research ISSN: 3108-0839 (Online)

Authors:- Pratik Mistry, Jayesh kumar Pitroda, DR. Sumit Phugat

Abstract:- This study discusses current advances in the use of nonablative and ablative lasers to improve medication absorption. This article carefully covers the ideas and enhancing processes of lasers, emphasising the technique's potential for dramatically improving medication absorption through the skin. To improve medication penetration, several wavelengths and kinds of lasers are used. The ruby laser, the erbium:yttrium:gallium:garnet laser, the neodymium-doped yttrium:aluminum:garnet laser, and the CO₂ laser are among them. A revolutionary approach for increasing topical/transdermal medication delivery is fractional modality. This possible application of the laser provides a new therapeutic for topical or transdermal application with high effectiveness. Further research with a large number of people or patients is required to confirm and clarify the findings in animal studies. Although the laser fluence or output energy used to enhance medication absorption is far lower than that used to treat skin problems and rejuvenation, the safety of employing lasers remains a concern.

Keywords:- Lasers, Transcellular, Ruby laser, Fractional laser, Photothermalwave.