Journal of Pharmaceutical Analysis and Drug Research ISSN: 3108-0839 (Online)

Authors: Deepak Gautam, Dr. Geeta Bhagwat

Abstract: Microsphere drug delivery is a novel approach of drug delivery for sustain and control the rate and release of active pharmaceutical ingredient. Microspheres are the choice of drug delivery for delivering the drug at specific site to release the encapsulated drug for treatment of various diseases. Microspheres drug delivery is an attractive dosage form in terms of its flexibility and sustaining the release as compare to other sustained and controlled formulation. Most of the antihyperlipidaemic drugs comes under BCS class-II which leads to poor solubility but higher permeability, oral bioavailability of statins categories drug possess less bioavailability due to poor solubility hence microspheres are the best candidate for delivering antihyperlipidaemic drugs to systemic circulation and improves the systemic bioavailability of drug for longer period of time with lesser adverse effects. Therefore microspheres can be used in various medical department like oncology, gynecology, radiology, pulmonary, cardiology, diabetes, vaccine therapy etc. this review article focuses on recent different methods of preparation. The microspheres formulated can be later evaluated and characterized by different procedure.