Authors : Dr. Rohan Mehta, Sneha Kapoor
Abstract: Green Analytical Chemistry (GAC) emphasizes sustainable, environmentally friendly approaches in pharmaceutical analysis. Traditional analytical methods often consume large volumes of organic solvents, generate hazardous waste, and have high energy demands. GAC aims to minimize environmental impact while maintaining accuracy, precision, and sensitivity. This paper reviews sustainable chromatography, analytical solvent-free techniques sample such as miniaturized preparation, solid-phase microextraction (SPME), and green spectrophotometric methods. The principles of GAC, method development strategies, and validation approaches are discussed. Tables summarize green analytical techniques, environmental benefits, and specific applications in pharmaceutical analysis. The paper highlights regulatory trends, challenges, and the future outlook for implementing sustainable analytical practices.
Keywords: Green analytical chemistry, sustainable analysis, pharmaceutical analysis, miniaturized chromatography, solid-phase microextraction, solvent reduction, method validation.
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