Pharmaceutical Interaction of Cephradine and Metformin HCL with Antimicrobial Activity Evaluation

Abstract

Cephradine and Metformin Hydrochloride (HCL) are commonly prescribed medications for the treatment of various medical conditions, including bacterial infections and type 2 diabetes, respectively. The co-administration of these drugs is not uncommon, particularly in patients with comorbidities. This research paper explores the interaction between cephradine and Metformin HCL. An in-depth analysis was conducted through in vitro studies. The primary objectives were to assess whether Metformin HCL has the potential to influence the pharmacokinetics of Cephradine. The results of revealed that Cephradine can indeed interact with Metformin HCL. These findings suggest that the concurrent use of Cephradine and Metformin HCL may necessitate dose adjustments or close monitoring to maintain therapeutic efficacy. It is essential to comprehend how cefuroxime and metformin HCL interact in order to maximize patient care and assure reliable and efficient treatment of diabetes and infectious disorders. This study clarifies the intricacy of medication interactions and emphasizes the value of interdisciplinary cooperation between medical specialists, such as doctors, pharmacists, and clinical pharmacologists, in order to develop customized treatment regimens that take into account both the recommended course of treatment and possible drug interactions.

KEYWORDS: Cephradine, Metformin Hydrochloride, Interactions, Zone of inhibition, Job’s plot