Journal of Research in Computer Science and Engineering ISSN: 2457-0818 (Online)

Authors:  Shraddha Pandey, Dr. Sudhakar Singh, Santosh Bahe

Abstract : For biological processes to occur, noncovalent interactions are essential. Everything from molecular recognition to molecular assembly to enzyme catalysis to the dynamic behaviour of biomolecules is aided by noncovalent interactions. Applications of noncovalent interactions have been increasingly important in recent years and are on the verge of becoming much more so in issues relating to a variety of fields of chemistry, biology, and physics. Due to their prevalence and high binding energy, noncovalent interactions that are dominated by electrostatic contributions have drawn the most attention. Electrostatic interactions have a wide spectrum and are directed. However, the directional components of electrostatic dominated noncovalent interactions have been completely ignored in the literature up to this point due to the fundamentally long range impactful nature of electrostatic contributions. To fully comprehend the electrostatic contributions, this thesis focuses on the significance and directional nature of long-range electrostatic interactions. In this chapter, we have provided a quick introduction of noncovalent bonds and their function in chemistry. In order to demonstrate how understanding of the significance of long-range electrostatic interactions has changed over time, we also went over a brief history of the scientific literature.

Keywords- Computer, Assessment, Science, Related to Materials, Bio-Materials