Vol 2, No 2 (2024)

Pharmacological Advances in Neuroprotection: Targeting Oxidative Stress in Neurodegenerative Diseases

Author: Shruti Desai

Abstract: Neurodegenerative diseases such as Alzheimer's, Parkinson's, and Huntington's disease are characterized by the progressive loss of neuronal function, often associated with oxidative stress as a core pathophysiological feature. This paper provides a comprehensive analysis of pharmacological strategies targeting oxidative stress to slow disease progression, focusing on antioxidant compounds, enzyme modulators, and emerging drug delivery systems. Additionally, it explores the role of genetic and epigenetic factors in the development of neuroprotective therapies. Through examining recent advancements in pharmacology and novel therapeutic avenues, this review underscores the potential for tailored neuroprotective treatments.

Keywords: Neuroprotection, Oxidative Stress, Neurodegenerative Diseases, Antioxidants, Pharmacology, Neuroprotective Agents, Alzheimer’s, Parkinson’s, Huntington’s Disease

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