Synthesis and Characterization of New Heterocyclic Compounds with Anticancer Potential

Abstract

Heterocyclic chemistry represents a cornerstone of modern medicinal chemistry, as the majority of therapeutic agents contain heterocyclic scaffolds. This paper explores the synthesis and characterization of novel heterocyclic compounds with potential anticancer activity. The synthetic route involves multi-step reactions including condensation, cyclization, and substitution using eco-friendly solvents and catalysts. Spectroscopic methods such as NMR, IR, and Mass spectrometry are utilized for structural elucidation. Biological screening against selected cancer cell lines reveals significant cytotoxic effects, attributed to enhanced molecular interactions with DNA and protein targets. Structure–activity relationship (SAR) studies demonstrate how small modifications in the heterocyclic core influence pharmacological potency. The study contributes to the ongoing development of safer and more effective anticancer agents through rational chemical design.

KEYWORDS: Heterocyclic compounds, Anticancer agents, Synthesis, SAR, Spectroscopic characterization